Hemolytic Anemia

Testcode:	ANAHAE
includes following tests:	Bilirubin, total (Serum (s)) Lactate dehydrogenase (LDH) (Serum (s)) CBC+diff. (EDTA blood (eb)) Reticulocytes (EDTA blood (eb)) Haptoglobin (Serum (s)) Coombs, direct (EDTA blood (eb)) Antibody screen (LISS/Coombs) (EDTA blood (eb))
Preanalytics/Notes:	Not offered outside of Germany due to limited sample stability of 24 hours.
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Interpretation:	Typical constellation in more… Typical constellation in hemolytic anemia: Low hemoglobin and erythrocyte count MCV is usually normal LDH elevated Bilirubin may be elevated Retikulozyten are usually increased Haptoglobin is low Coombs-Test (DCT - direct Coombs Test) may be positive Irregular antibodies may be found Hemolytic anemias can be differentiated into corpuscular hemolytic anemias: spherocytosis sickle cell anemia thalassemia PNH (paroxysmal nocturnal hemoglobinuria) glucose-6-phosphate-dehydrogenase deficiency (favism) and extracorpuscular hemolytic anemias: autoimmune hemolytic anemia (AIHA) TTP, HUS transfusion reaction / complication hemolytic disease of the fetus / newborn artificial cardiac valves close