CBC+diff. (EDTA blood (eb))

Specimens:	EDTA blood (eb)
includes following tests:	Hemogram (CBC) (EDTA blood (eb))
Preanalytics/Notes:	To avoid clotting please mix test tube carefully several times directly after collection of blood.
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Duration:	1 day
Indication/Significance:	The blood count is frequently an integral part of a basic examination, e.g. check patients Suspected anaemia Diagnosis of polycythaemia Suspected leukaemia/Suspected pancytopenia Therapy monitoring e.g. with chemotherapy The blood count without differential test comprises the determination of the number of erythrocytes, leucocytes and thrombocytes, of haemoglobin, haematocrit and different indices such as MCV and MCH. With the complete blood count, the leucocytes are additionally differentiated according to neutrophilic, eosinophile and basophile granulocytes as well as lymphocytes and monocytes. For reasons of greater accuracy, the counting is carried out by a machine. If abnormalities are detected during the automatic analysis, a microscopic examination of the smear will be carried out in addition. A manual smear examination for microscopic differentiation can also be requested separately, especially if there is a specific suspicion of a haematological disease. Note: With asymptomatic patients (e.g. check patients), a blood count leads to a new diagnosis in no more than one in every 200 cases. Therefore, it is frequently a subject of discussion in literature and at congresses whether this blood screening is indicated at all with symptomatic patients.
Interpretation:	Blood count without more… Blood count without differential: Reduced or increased leucocytes: Leucocytopenia/leucocytosis (e.g. suspected leukaemia) Reduction of the number of erythrocytes and the haemoglobin level: Anaemia; the indices MCV and MCH allow for a practice-oriented classification of the form of anaemia resulting in a targeted diagnosis. See keyword "Anaemia diagnosis" Reduced or increased number of thrombocytes: Thrombocytopenia or thrombocytosis Differential blood count: Unreife Vorstufen (IMGRAN oder IG) können bei schweren Entzündungen vorkommen: < 5 %. A higher proportion can be an indication of a haemoblastosis, see table 4. An increase of so-called stab cell granulocytes is an indication of a reactive left shift, e.g. with bacterial infections. Lymphatic stimulus forms, so-called lymphomononuclear cells can be an indication of a viral infection, e.g. mononucleosis (Pfeiffer's disease). The decrease or increase of thrombocytes, e.g. in the microscopically evaluated smear, confirm a thrombocytopenia or thrombocytosis; the verification of thrombocyte agglutinates can indicate a pseudothrombocytopenia. Erythrocytes can be assessed according to the cell size, cell colour and cell shape. Different erythrocyte shapes can indicate diseases or support or confirm tentative diagnoses, e.g. spherocytes as an indication of hereditary spherocytosis (spherocytic anaemia); fragmented red blood cells (schistocytes) are helmet-like or eggshell-like erythrocyte fragments as a possible indication of a mechanical destruction of erythrocytes, e.g. after cardiac valve replacement or haemolytic-uraemic syndrome (HUS). Erythrocytes with basophilic stippling (precipitated ribosomal RNA) are signs of a disturbed regeneration of erythropoiesis (e.g. saturnine poisoning). close
Further tests:	Further haematological diagnostics

CBC+diff. (EDTA blood (eb))

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