Vitamin K1 (HPLC) (s) (Serum, frozen (s))

Testcode:	E_VITK
Specimens:	2 ml Serum, frozen (s)
Preanalytics/Notes:	Send samples protected from light (e. g. wrapped with foil). Serum stable for 24h, otherwise freeze the sample.
Method:	HPLC
Dimension:	ng/l
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Duration:	8 days
Indication/Significance:	Suspected vitamin K deficiency in the case of Disturbed fat absorption, e.g. with pancreatic insufficiency, cholestasis, coeliac disease Reduced absorption with food with simultaneously reduced synthesis in the intestines (new-borns, intensive care patients treated with antibiotics)
Interpretation:	Vitamin K is necessary more… Vitamin K is necessary for the activation of the coagulations factors II, VII, IX, X and for the synthesis of protein C and S. A deficiency can result in a bleeding tendency (reduced Quick value). If there is a vitamin K deficiency, the other fat-soluble vitamins A, D and E should also be checked. Overdoses lead to increased concentrations, but not to clinical symptoms and are thus not clinically relevant. Note: The fat-soluble vitamin K is especially contained in green plants (e.g. Brussel sprouts, cauliflower, kale, spinach, broccoli) and is additionally produced by intestinal bacteria. A deficiency thus especially develops if the fat absorption is disturbed (e.g. pancreatic insufficiency, cholestasis, coeliac disease). close
Further tests:	Vitamins A, D and E

both sex
	320 - 1000 ng/l