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Vitamin D (25) (Serum (s))

Testcode:	E_VIT25D
Specimens:	500 µl Serum (s)
Preanalytics/Notes:	Information for sampling: Diagnosing of a vitamin D deficiency is particularly useful in the months January to April due to the reduced exposure to sunlight. Stop vitamin D supplementation at least 24 hours before blood collection
Method:	CLIA
Dimension:	ng/ml
Alternate dimension:	nmol/l (Factor: 2.5) Calculator
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Duration:	1 day
Indication/Significance:	Vitamin D deficiency in the case of: Sunlight deficit Reduced enteral uptake Increased metabolism (barbiturate inter alia) Increased loss (e.g. dialysis) Disorders of the calcium metabolism Reduced bone density
Interpretation:	Decreased: Vitamin D more… Decreased: Vitamin D deficiency caused by Lack of exposure to sun, especially in elderly persons and home residents, due to clothing (e.g. habit) Malnutrition, malabsorption, e.g. coeliac disease/sprue Increased vitamin D requirement in children, growth (e.g. in combination with UV deficit), pregnancy and lactation Increased metabolism: e.g. anti-epileptic agents (diphenylhydantoin and barbiturate), possible in the case of primary hyperparathyroidism Renal losses, nephrotic syndrome, dialysis Increased: Overdosing Distinct exposure to UV light Diagnosing of a vitamin D deficiency is particularly useful in the months January to April due to the reduced exposure to sunlight. With regard to a sufficient vitamin D supply, a 25-hydroxy vitamin D level of > 30 ng/ml (>75 nmol/l) is aimed for (Clin.Lab.2006, 52: 335-343) close
Further tests:	1.25-dihydroxycholecalciferol, parathormone, calcium and phosphate

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Reference range / valuation (openclose)

both sex
	20,0 - 100,0 ng/ml
Deficiency <20 ng/ml (<50 nmol/l) Optimal 30-50 ng/ml (75-125 nmol/l) Risk of toxicity >100 ng/ml (>250 nmol/l) Concentration in nmol/l corresponds to concentration in ng/ml x factor 2.5. Source: (Nutrients 2023, 15, 695. https://doi.org/10.3390/nu15030695)

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Calculator for Vitamin D (25)

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