Vitamin B12 (cobalamine) (Serum (s), frozen)
| Testcode: | E_VITB12 |
| Specimens: | 500 µl Serum (s), frozen |
| Preanalytics/Notes: | Let blood sample coagulate after sampling, centrifuge, transfer serum into a new tube and label the tube accordingly. Freeze if the transport time is longer than 24 hours. Patients receiving high doses of biotin (> 5 mg / day) should be sampled at least 8 hours after the last application, as high levels of biotin may interfere with the test system. |
| Method: | ECLIA |
| Dimension: | pg/ml |
| Alternate dimension: | pmol/l (Factor: 0.738) Calculator |
| Set-up: | Mon Tue Wed Thu Fri Sat Sun |
| Duration: | 2 days |
| Indication/Significance: |
A determination of vitamin B12 is only appropriate if no vitamin B12 preparations were taken weeks to months before. |
| Interpretation: |
Decreased: Alimentary more… Decreased:
Increased:
The determination of vitamin B12 is of limited specificity and sensitivity for the measurement of the vitamin B12 status, especially with concentrations below 300 pg/ml. Signs of a clinical vitamin B12 deficiency can also be found in patients with vitamin B12 concentrations in the lower reference range (< 300 pg/ml). In these patients with levels of 150 - 300 pg/ml, holotranscobalamin should be determined additionally. For an optimum homocysteine level, the vitamin B12 level should be above 340 pg/ml. |
| Further tests: | Determination of folic acid, holotranscobalamin, methylmalonic acid (MMA) |
performance by Bioscientia medical service centers
Reference range / valuation (openclose)
| both sex | ||
|---|---|---|
| 197 - 771 pg/ml | ||
initial letter
Abrechnung GOÄ
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