Thyroid peroxidase antibodies (TPO abs) (Serum (s))

Specimens:	500 µl Serum (s)
Preanalytics/Notes:	Autoantibodies against thyroid peroxidase (anti-TPO) see also thyroglobulin antibodies (TAK). Patients receiving high doses of biotin (> 5 mg / day) should be sampled at least 8 hours after the last application, as high levels of biotin may interfere with the test system.
Method:	ECLIA
Dimension:	IU/ml
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Duration:	1 day
Indication/Significance:	TSH increase of unknown cause Struma of unknown aetiology Hypothyreosis of unknown aetiology Suspected polyglandular auto-immune disease Familial auto-immune thyroid disease Risk assessment of the development of a hyperthyreosis during therapy with drugs that can also impair the thyroid gland, e.g. lithium salts, amiodarone, alpha-interferon and interleukin-2 Risk assessment of the development of a hypothyreosis in the case of Down's syndrome Risk assessment of the development of a functional disorder of the thyroid gland during pregnancy and a postpartal thyroiditis Prior to treatment of a subclinical hypothyreosis
Interpretation:	Increased in the case more… Increased in the case of: Hashimoto's thyroiditis (in 80-90 % of the cases) Basedow's hyperthyreosis (70-80 %) Struma/hypothyreosis (up to 20 %) Thyroid carcinoma (approx. 20 %) Polyendocrinopathies I and II Patients with amiodarone therapy (in 14-18 % of the cases) close
Further tests:	Tg antibodies (TAK), TRAK

both sex
	< 34 IU/ml