Specimens: | 500 µl Cerebrospinal fluid (csf) |
Preanalytics/Notes: | Please send frozen csf in a separate polypropylene tube (PP). Glass or polystyrene tubes (PS) can lead to false low results. Unfrozen material will be frozen upon receipt. |
Method: | ELISA |
Dimension: | pg/ml |
Set-up: | Mon Tue Wed Thu Fri Sat Sun |
Duration: | 10 days |
Indication/Significance: | Suspected neurodegenerative disease. |
Interpretation: |
Total tau protein more… Total tau protein is considered a process marker in CNS disorders and is increased in a variety of neurological disorders. Tau protein is characteristic for neuronal degeneration in the central nervous system. Increaed csf concentration is associated with:
The highest tau concentrations are present in Creutzfeldt-Jakob disease (Creutzfeldt-Jakob-Disease, CJD) and cerebral infarction. Results >1200 pg/ml can indicate CJD. The reference values are not valid for people with Trisomy 21. This genetic defect lowers the (phospho-)tau values, ¿¿so that the typically elevated tau proteins in Alzheimer's disease are incorrectly low. |
Further tests: |
|
both sex | ||
---|---|---|
< 290 pg/ml |
Die Kosten werden für den i. d. R. genutzten 1,15-fachen GOÄ-Satz dargestellt. Wird die Untersuchung nicht in Ihrem regionalen Labor durchgeführt, erfolgt die Analyse in dem Labor, das im Leistungsverzeichnis genannt ist. In diesem Fall gilt der dort für die Untersuchung angegebene Preis.