Pyridinoline structure (HPLC) (Urine (u))

Testcode:	E_PYRIDB
Specimens:	5 ml Urine (u)
includes following tests:	Pyridinoline (Urine (u)) Desoxypyridinoline (Urine (u))
Preanalytics/Notes:	Please send spontaneous urine (2nd morning urine) or 10 ml of a 24 h urine, protected from light and deep-frozen. Please note: for these parameters the analysis of creatinine in urin is necessary and will be charged off.
Method:	HPLC
Set-up:	on demand
Duration:	8 days
Indication/Significance:	Diagnostic assessment and follow up of an increased turnover of organic bone matrix (osteoporosis) Diagnostic assessment of an increased PYD/DPD ratio with increased cartilage degradation, e.g. arthritis, arthrosis
Interpretation:	Marker of increased more… Marker of increased turnover of organic bone matrix with broad intra- and inter-individual variation by Circadian rhythm Physical activity or immobilization hormonal status close
Further tests:	Alkaline phosphatase, calcium, bone phosphatase, osteocalcine, crosslaps, collagen-type I-telopeptides (NTx and CTx), 25-OH-cholecalciferol, 1,25-dihydroxy-cholecalciferol

sample referred to a partner lab