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Protein S 100 (s) (Serum, frozen (s))

Specimens:	1 ml Serum, frozen (s)
Preanalytics/Notes:	Let whole blood coagulate after sampling, centrifuge and transfer supernatant serum into a new tube, label the tube accordingly, freeze and dispatch frozen. Patients receiving high doses of biotin (> 5 mg / day) should be sampled at least 8 hours after the last application, as high levels of biotin may interfere with the test system.
Method:	ECLIA
Dimension:	µg/l
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Duration:	1 day
Indication/Significance:	Differential diagnostics in the case of CUP (cancer of unknown primary) Tumour markers for malignant melanoma to estimate the prognosis, to monitor the efficiency of therapy and for follow-up Neurological indications e.g. as destruction parameters for the assessment of organic brain damages such as hypoxia, after resuscitation, cerebral contusion Diagnosis of dementia in the liquor and detection in the case of prion disease (e.g. Creutzfeld-Jakob disease)
Interpretation:	Elevated concentrations more… Elevated concentrations of protein S 100 in the serum can be an indication of a generalised organic brain damages, e.g. in the case of hypoxia, after resuscitation, in the case of cerebral contusion, in the case of cerebrocranial traumas. Elevated protein S 100 levels in the liquor can occur with all acute cerebral lesions. An early determination of protein S 100 after acute cerebral lesions is recommended to estimate the prognosis and, in the event of negative computer tomographic findings, to assess the cerebral involvement. Close-meshed serial analyses may be useful as an additional criterion for the assessment of the progress. Within the scope of a diagnostic assessment of dementia, significantly increased concentrations are indicative of dementia. close
Further tests:	Tau protein or beta amyloid in the liquor

Reference range / valuation (openclose)

both sex
	< 0,11 µg/l

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Abrechnung GOÄ

Die Kosten werden für den i. d. R. genutzten 1,15-fachen GOÄ-Satz dargestellt. Wird die Untersuchung nicht in Ihrem regionalen Labor durchgeführt, erfolgt die Analyse in dem Labor, das im Leistungsverzeichnis genannt ist. In diesem Fall gilt der dort für die Untersuchung angegebene Preis.