Protein C activity (Citrated plasma, frozen (cp))

Testcode:	E_PCAKT
Specimens:	1 ml Citrated plasma, frozen (cp)
Preanalytics/Notes:	To avoid clotting please mix test tube carefully several times directly after collection of blood. Please centrifuge sample immediately, at least for 15 minutes (1500 x g). Plasma / supernatant should be transferred by pipette to a collection tube without any buffer or other substances. Please label as citrated plasma. Freeze and send frozen. No blood sampling from central venous catheter. If additional coagulation tests are ordered (e.g. factor II - XIII), at least one extra tube of frozen citrated plasma is needed.
Method:	Chromogenic assay
Dimension:	%
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Duration:	2 days
Indication/Significance:	Thrombophilia screening Consumptive coagulopathy Monitoring of replacement therapy with protein C concentrate
Interpretation:	Decreased: Hereditary more… Decreased: Hereditary protein C deficiency Heterozygous protein C deficiency: Protein C activity 20 - 70 % Homozygous protein C deficiency: Protein C activity < 1 % No strict correlation between protein C concentration and thromboembolic complication rate Acquired protein C deficiency: Vitamin K deficiency, diseases of the hepatic parenchyma, consumptive coagulopathy Increased: Lupus anticoagulant Pregnancy Heparin therapy close
Further tests:	Thrombophilia parameters

Representation of age: "from" refers to the commenced year(s) (month) of age; "until" refers to the completed year(s) (month) of age.