| Testcode: | E_PIGF |
| Specimens: | 500 µl Serum (s), frozen |
| Preanalytics/Notes: | The samples should be sent to the laboratory promptly and they need to be frozen for a longer storage. In patients undergoing therapy with high doses of biotin (> 5 mg/day), samples should be taken at least 8 hours after administration, as high doses of biotin can interfere with PLGF determination.
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| Method: | ECLIA |
| Dimension: | pg/ml |
| Set-up: | Mon Tue Wed Thu Fri Sat Sun |
| Duration: | 2 days |
| Indication/Significance: | Risk of preeclampsia in pregnant women (from the 20th week of pregnancy at the earliest): - The sFlt 1/PlGF ratio is used to support the short-term prediction of preeclampsia (exclusion and inclusion) in pregnant women with suspected preeclampsia in conjunction with other diagnostic and clinical information. |
| Interpretation: |
The concentration ratio more… The concentration ratio between the anti-angiogenic factor sFlt-1 and the angiogenic factor PlGF is currently considered the most sensitive indication of an imminent pre-eclampsia. This quotient allows for a prediction up to 5 weeks before the onset of the disease. A sensitivity of 85 % with a specificity of 95 % was described for all forms of pre-eclampsia, whether mild or severe. |
Die Kosten werden für den i. d. R. genutzten 1,15-fachen GOÄ-Satz dargestellt. Wird die Untersuchung nicht in Ihrem regionalen Labor durchgeführt, erfolgt die Analyse in dem Labor, das im Leistungsverzeichnis genannt ist. In diesem Fall gilt der dort für die Untersuchung angegebene Preis.