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Methotrexate (Serum (s))
| Specimens: | 500 µl Serum (s) |
| Preanalytics/Notes: | Blood collection 24, 48 or 72 hours after beginning of infusion (administration), delayed further elimination if necessary.Please note that when using gel-containing tubes the results may be lower.Blood centrifuge 30 min after removal, separate serum and transfer into a new tube.Keep the serum protected! |
| Method: | ELISA |
| Dimension: | µmol/l |
| Set-up: | Mon Tue Wed Thu Fri Sat Sun |
| Duration: | 1 day |
| Indication/Significance: | Monitoring of methotrexate therapy. |
| Interpretation: |
Methotrexate is excreted more… Methotrexate is excreted renally by approx. 80%.Exceeding these limits increases the risk of toxic side effects (hemato-, hepato-, nephrotoxic). |
Reference range / valuation (openclose)
| both sex | ||
|---|---|---|
|
Guide values after high dose-chemotherapy: after 24h: < 10 µmol/l after 48h: < 1 µmol/l after 72h: < 0.1 µmol/l |
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Abrechnung GOÄ
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