Glucose-6-Phosphate-Dehydrogenase (EDTA blood (eb))
| Testcode: | E_G6PDB |
| Specimens: | 1000 µl EDTA blood (eb) |
| Preanalytics/Notes: | Reticulocytes show higher enzyme activities than mature erythrocytes. The determination of G-6-PD after severe haemolytic crises can therefore lead to high G-6-PD activities due to the increased reticulocyte count and thus mask a G-6-PD deficiency. A G-6-PD deficiency can also be overlooked in the presence of hypochromic anemia or a strong leukocytosis (too high enzyme activity relative to the Hb concentration per erythrocyte or G-6-PD activity of the leukocytes). Please send refrigerated at 2-8 C°. Do not freeze. |
| Method: | Photometric assay |
| Dimension: | U/gHb |
| Set-up: | Mon Tue Wed Thu Fri Sat Sun |
| Duration: | 5 days |
| Indication/Significance: |
|
| Interpretation: |
Increased: With more… Increased:
Decreased:
The G6PD deficiency is the most common erythrocyte enzyme deficiency and a possible cause of a congenital haemolytic anaemia. It is particularly common in Mediterranean countries, Africa and Asia. The enzyme deficiency and the corresponding clinical symptoms can vary significantly. The development of a haemolytic crisis caused by triggering factors such as infections, medication (e.g. sulphonamides, analgesics) and the consumption of fava (tic) beans is typical. The majority of carriers shows no symptoms beyond these crises. It must be taken into consideration that young erythrocytes have an increased enzyme activity. In some circumstances, this could feign false normal values for G6PD within the scope of a haemolytic crisis.An analysis in the latent stage is thus advisable. |
sample referred to a partner lab
Reference range / valuation (openclose)
| both sex | ||
|---|---|---|
| 7,00 - 20,50 U/gHb | ||
initial letter
Abrechnung GOÄ
Die Kosten werden für den i. d. R. genutzten 1,15-fachen GOÄ-Satz dargestellt. Wird die Untersuchung nicht in Ihrem regionalen Labor durchgeführt, erfolgt die Analyse in dem Labor, das im Leistungsverzeichnis genannt ist. In diesem Fall gilt der dort für die Untersuchung angegebene Preis.