Gliadine DP abs. (Serum (s))

Specimens:	1 ml Serum (s)
includes following tests:	Gliadine DP abs. (IgA) (Serum (s)) Gliadine DP abs. (IgG) (Serum (s))
Set-up:	on demand
Duration:	3 days
Indication/Significance:	Suspected idiopathic sprue (gluten-induced enteropathy, coeliac disease) Therapy monitoring in the case of a gluten-free diet Differential diagnostics of malabsorption syndromes Failure to thrive in children
Interpretation:	Increased in the case more… Increased in the case of: Gluten-sensitive enteropathy in children Coeliac disease in adults Herpetiform dermatitis Other bowel diseases in adults The gliadin antibody test is carried out to detect or rule out a coeliac disease, usually together with the transglutaminase antibody test (endomysium antibodies). IgA DGP antibodies are the best markers in children under the age of two. As patients with coeliac disease often have an IgA deficiency, the determination of IgG DGP antibodies is important. An appropriate rational procedure could be as follows (also in patients with IgA deficiency!): IgG/IgA DGP antibodies and transglutaminase IgA antibodies. The measurement of the IgA concentration in the serum is indicated in addition. The antibody titers drop on a gluten-free diet and are usually no longer detectable after 6 months. close
Further tests:	Transglutaminase (endomysium) - IgA antibodies (tTg/TG2), IgA, EMA antibodies (IFT), HLA-DQ2 and HLA-DQ8