Erythropoetin (EPO) (Serum (s))

Testcode:	E_EPOS
Specimens:	500 µl Serum (s)
Preanalytics/Notes:	Because of daily fluctuations Blood sampling in the morning (8.00 - 10.00 clock). Patients receiving high doses of Biotin (> 5 mg/day) should be sampled at least 8 hours after the last aplication, as high levels of the Biotin may interfere with the test system.
Method:	CLEIA
Dimension:	mIU/ml
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Duration:	1 day
Indication/Significance:	DD of renal and non-renal anaemias Polycythaemia diagnostics Therapy control in the case of EPO substitution
Interpretation:	Increased: Reactive in more… Increased: Reactive in the case of hypoxia Paraneoplastic increase, e.g. renal cell carcinoma Decreased: Renal insufficiency Polycythaemia vera close

both sex
	4,3 - 29,0 mIU/ml
hemoglobin-related serum EPO: 20th-80th percentile reference range: (mIU/ml): Hb < 8 g/dl [4.96 mmol/l] 51 - 312 Hb 8 - 9 g/dl [4.96 - 5.59 mmol/l] 35 - 205 Hb 9 - 10 g/dl [5.59 - 6.21 mmol/l] 27 - 95 Hb 10 - 11 g/dl [6.21 - 6.83 mmol/l] 19 - 59 Serum EPO concentrations below the 20th percentile are consistent with an insufficient EPO secretion in relation to the hemoglobin value.