APC resistance (Citrated plasma, frozen (cp))

Testcode:	E_APCAC
Specimens:	2 ml Citrated plasma, frozen (cp)
Preanalytics/Notes:	To avoid clotting please mix test tube carefully several times directly after collection of blood. Please centrifuge sample immediately, at least for 15 minutes (1500 x g). Plasma / supernatant should be transferred by pipette to a collection tube without any buffer or other substances. Please label as citrated plasma. Freeze and send frozen. No blood sampling from central venous catheter. If additional coagulation tests are ordered (e.g. factor II - XIII), at least one extra tube of frozen citrated plasma is needed.
Method:	Turbidimetry
Dimension:	Ratio
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Duration:	2 days
Indication/Significance:	The most important parameter within the scope of thrombophilia screening Also if oral contraceptives or other medications containing oestrogen are prescribed for the first time in the case of a respective family case history
Interpretation:	Decreased in the case more… Decreased in the case of: Factor V Leiden mutation, acquired APC resistance close
Further tests:	Factor V Leiden gene mutation test

both sex
		cut-off: > 2.2