Anti-mitochondrial abs (AMA) (IFT) (Serum (s))

Testcode:	E_AMAQL
Specimens:	1 ml Serum (s)
Method:	Indirect immunofluorescence assay
Dimension:	Titer
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Duration:	1 day
Indication/Significance:	Diagnostic assessment of: Primary biliary cirrhosis (PBC): especially by means of subtype M2 Chronic hepatis Icterus Drug-induced LE Mitochondrial antibodies subtype M2 is important for the diagnosis of PBC. Subtype 2 antibodies are antibodies against the target antigen "pyruvate dehydrogenase (PDH)".
Interpretation:	Evidence of positive more… Evidence of positive antibodies with: Primary biliary cirrhosis (PBC) 95 % Pseudo-LE syndrome 100 % Chronic hepatitis with cholestasis 30 % Cryptogenic cirrhosis 30 % Systemic LE 10 % Sjögren's syndrome 5 % Healthy persons < 1 % Elevated values of subtype 2 indicate a PBC. In the case of subtype 2, antibodies against pyruvate dehydrogenase, the main antigen of AMA, are detected. Such increased antibody concentrations can occur prior to clinical symptoms. Therefore, the clinical significance should always be assessed in connection with pathological liver findings (AP activity). close

both sex
	< 1:100 Titer