Galactose (NaF) (NaF plasma (NaF))

Testcode:	GALA_H
Specimens:	1 ml NaF plasma (NaF)
Method:	UV test
Dimension:	mg/dl
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Duration:	4 days
Indication/Significance:	Diagnostic assessment of a liver dysfunction in new-borns at the end of the first week of life (accumulation of galactose-1-phosphate when fed with milk) Control of the metabolic adjustment (galactose-1-phosphate in erythrocytes is suitable, for example)
Interpretation:	Elevated values for free more… Elevated values for free galactose or for galactose-1-phosphate as well as low enzyme activity are consistent with a clinically manifested galactosaemia. The activity of galactose-1-phosphate uridyltransferase in patients with classical galactosaemia is usually < 2 % of the standard. When fed with milk, a severe liver dysfunction develops by the end of the first week of life as a result of the accumulation of toxic metabolites (galactose-1-phosphate). With a lactose-free diet, the acute symptoms rapidly disappear. In the long-term, however, chronic damage of the CNS and the ovaries may occur despite a permanent lactose-free diet. The cause of this is the endogenous synthesis of galactose. The determination of galactose-1-phosphate in erythrocytes is a control parameter for a good metabolic adjustment. close

sample referred to a partner lab

both sex
from 0 - 3 Weeks	< 10,0 mg/dl
from 4 Weeks - 120 Years	< 4,3 mg/dl

Representation of age: "from" refers to the commenced year(s) (month) of age; "until" refers to the completed year(s) (month) of age.