Aldosterone (EP) (EDTA blood (eb))

Specimens:	500 µl EDTA blood (eb)
Method:	CLIA
Dimension:	ng/dl
Alternate dimension:	pmol/l (Factor: 27.7) Calculator
Set-up:	Mon Tue Wed Thu Fri Sat Sun
Duration:	1 day
Indication/Significance:	Clinical significance: Diagnosis of hyperaldosteronism Diagnosis and differentiation of hyperaldosteronism in combination with renin and functional tests Detection of a mineralocorticoid deficiency Primary hyperaldosteronism (PHA) is a common cause of arterial hypertonia. Its prevalence is 5 to 13 percent in hypertensive patients. Up to 90 % of all patients are normokalaemic, thus the absence of a hypokaliaemia in no way rules out a PHA. The determination of the aldosterone/renin ratio (ARR) is the best screening test. With a pathological ARR, a confirmatory test is indicated, whereby the sodium chloride test is to be preferred. The further clarification is done by means of complementary biochemical and imaging procedures. As the PHA is a potentially curable disease, a general screening is currently also recommended in normokalaemic hypertensive patients if more then two antihypertensive agents are required
Interpretation:	Increases:Primary more… Increases:Primary hyperaldosteronism in NNR adenoma (Conn syndrome) or adrenal hyperplasia (uni- or bilateral)secondary hyperaldosteronism, e.g. Renin-producing tumorsDecreased in:hypoaldosteronismM. Addison close
Further tests:	Renin (EDTA plasma) with aldosterone renin ratio (ARQ), aldosterone in the urine

both sex
0 Years	5,0 - 132,0 ng/dl
from 1 Year - 20 Years
Currently there are no reference ranges for this age. The reference range for patients aged 21 - 65 can be used for orientation: 2.2 - 35.3 ng/dl [61 - 978 pmol/l] (30 min. upright position, blood drawing 7 - 10 am) 1.2 - 23.6 ng/dl [33 - 654 pmol/l] (30 min. in supine position, blood drawing 7 - 10 am)
from 21 Years - 64 Years	2,2 - 35,3 ng/dl
2.2 - 35.3 ng/dl [61 - 978 pmol/l] (30 min. upright position, blood drawing 7 - 10 am) 1.2 - 23.6 ng/dl [33 - 654 pmol/l] (30 min. in supine position, blood drawing 7 - 10 am)
from 65 Years - 120 Years
Currently there are no reference ranges for this age. The reference range for patients aged 21 - 65 can be used for orientation: 2.2 - 35.3 ng/dl [61 - 978 pmol/l] (30 min. upright position, blood drawing 7 - 10 am) 1.2 - 23.6 ng/dl [33 - 654 pmol/l] (30 min. in supine position, blood drawing 7 - 10 am)

Representation of age: "from" refers to the commenced year(s) (month) of age; "until" refers to the completed year(s) (month) of age.